Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25289195 | 0.87 | CNR1 (0.39) | KMT2ALMNAMAPTCNR1CNR2 | |
| SCHEMBL30496268 | 0.87 | CNR1 (0.39) | KMT2ALMNAMAPTCNR1CNR2 | |
| SCHEMBL31369008 | 0.83 | KMT2A (0.50) | KMT2ALMNAMAPTALDH1A1MAPK1 | |
| SCHEMBL30496247 | 0.81 | GPR119 (0.38) | KMT2ALMNAMAPTCNR1CNR2 | |
| SCHEMBL25282720 | 0.81 | GPR119 (0.38) | KMT2ALMNAMAPTCNR1CNR2 | |
| SCHEMBL8840383 | 0.79 | POLB (0.57) | KMT2ALMNAMAPTNPSR1ALDH1A1 | |
| SCHEMBL22866604 | 0.77 | CNR1 (0.44) | KMT2ALMNAMAPTCNR1CNR2 | |
| SCHEMBL10329947 | 0.76 | SMN1; SMN2 (0.41) | KMT2ANPSR1CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL900419 | 0.75 | ALDH1A1 (0.58) | KMT2ALMNAMAPTALDH1A1MAPK1 | |
| SCHEMBL6652987 | 0.75 | KMT2A (0.45) | KMT2ALMNAMAPTNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219973-A1 | DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF | MOLECURE S.A. (PL) | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219973-A1 | DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF | USP7, USP28, USP1 | KMT2A 884/4885LMNA 3209/4885MAPT 1555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.