Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | VNN1 | O95497 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16517596 | 0.86 | VNN1 (0.41) | ADORA2AADORA1VNN1SMN1; SMN2POLB | |
| SCHEMBL16534321 | 0.78 | CCNC (0.41) | NAMPT | |
| SCHEMBL24510177 | 0.78 | KDM5B (0.40) | VNN1KDM4C | |
| SCHEMBL23445929 | 0.78 | RECQL (0.42) | ADORA2AADORA1RECQLSMN1; SMN2POLB | |
| SCHEMBL25087065 | 0.77 | LOXL2 (0.46) | VNN1MBOAT4CYP2C9CYP2C19MAPK1 | |
| SCHEMBL25044387 | 0.76 | RAB9A (0.44) | RECQLSMN1; SMN2POLB | |
| SCHEMBL29129138 | 0.75 | VNN1 (0.38) | ADORA2AADORA1VNN1MBOAT4GRM4 | |
| SCHEMBL16532586 | 0.73 | MBOAT4 (0.43) | VNN1MBOAT4CYP2C19KDM4CMAPK1 | |
| SCHEMBL7666624 | 0.73 | MBOAT4 (0.40) | VNN1MBOAT4GRM4CYP2C19KDM4C | |
| SCHEMBL481078 | 0.73 | NOTUM (0.43) | VNN1RECQLMBOAT4GRM4KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023121992-A1 | CYCLOPROPYL COMPOUNDS | ICAGEN, LLC (US) | 2023-06-29 | — | — | WO | disclosed |