Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23446458 | 0.85 | NPSR1 (0.50) | SMN1; SMN2MALT1KMT2AALOX15ALDH1A1 | |
| SCHEMBL25044387 | 0.81 | RAB9A (0.44) | RECQLSMN1; SMN2POLBKMT2ANPC1 | |
| SCHEMBL23445930 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2CYP2C9CYP2C19KMT2AALDH1A1 | |
| SCHEMBL25880492 | 0.78 | ADORA2A (0.42) | RECQLSMN1; SMN2POLBCYP2C9CYP2C19 | |
| SCHEMBL8122072 | 0.77 | GABRP (0.41) | POLBKMT2AKDM4E | |
| SCHEMBL357801 | 0.75 | SMN1; SMN2 (0.73) | SMN1; SMN2POLBKMT2AALOX15ALDH1A1 | |
| SCHEMBL10061637 | 0.74 | MAPK13 (0.40) | POLBKMT2AALOX15ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL27694741 | 0.74 | SMN1; SMN2 (0.71) | SMN1; SMN2POLBKMT2AALOX15ALDH1A1 | |
| SCHEMBL509374 | 0.73 | KDM5B (0.50) | SMN1; SMN2POLBKMT2ANPC1RAB9A | |
| SCHEMBL5757316 | 0.73 | RAB9A (0.39) | SMN1; SMN2KMT2AALDH1A1ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021105474-A1 | NEW COMPOUNDS FOR TREATMENT OF DISEASES RELATED TO DUX4 EXPRESSION | Facio Intellectual Property B.V. (NL) | 2021-06-03 | — | — | WO | disclosed |