Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2819616 | 0.89 | ALDH1A1 (0.41) | CA2ALDH1A1PKMTDP1 | |
| SCHEMBL25880955 | 0.82 | ALDH1A1 (0.39) | ALDH1A1PKMTDP1 | |
| SCHEMBL25881122 | 0.78 | KMT2A (0.42) | ALDH1A1PKMTDP1 | |
| SCHEMBL25881070 | 0.73 | ALDH1A1 (0.40) | ALDH1A1PKMTDP1 | |
| SCHEMBL25880959 | 0.71 | DUT (0.33) | ALDH1A1PKM | |
| SCHEMBL23748091 | 0.68 | TDP1 (0.39) | CA2TDP1 | |
| SCHEMBL30951365 | 0.68 | TDP1 (0.39) | CA2TDP1 | |
| SCHEMBL25889848 | 0.67 | ALDH1A1 (0.33) | ALDH1A1PKM | |
| SCHEMBL28561383 | 0.67 | KMT2A (0.48) | ALDH1A1TDP1 | |
| SCHEMBL31201645 | 0.66 | ALDH1A1 (0.47) | ALDH1A1PKMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227474-A1 | COMPOSITIONS AND METHODS FOR CORRECTION OF ABERRANT SPLICING | SKYHAWK THERAPEUTICS, INC. (US) | 2023-07-20 | — | — | US | disclosed |
| US-20230227474-A1 | COMPOSITIONS AND METHODS FOR CORRECTION OF ABERRANT SPLICING | SKYHAWK THERAPEUTICS, INC. (US) | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227474-A1 | COMPOSITIONS AND METHODS FOR CORRECTION OF ABERRANT SPLICING | RBM17, SF3B1, SF3B5 | CA2 4876/4885ALDH1A1 3962/4885PKM 2138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.