Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALPG | P10696 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | BCL6 | P41182 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | PRKCG | P05129 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25876087 | 0.76 | MEN1 (0.60) | MAPTKDM4ERAB9AMEN1ALPG | |
| SCHEMBL25310959 | 0.75 | RAB9A (0.64) | MAPTKDM4ERAB9AMEN1ALPG | |
| SCHEMBL29466342 | 0.75 | RAB9A (0.64) | MAPTKDM4ERAB9AMEN1ALPG | |
| SCHEMBL28546720 | 0.75 | CYP1A2 (0.64) | MAPTKDM4ERAB9AMEN1ALPG | |
| SCHEMBL3759875 | 0.73 | MAPT (1.00) | MAPTKDM4ERAB9AMEN1ALPG | |
| SCHEMBL25876316 | 0.72 | MAPT (0.60) | MAPTKDM4ERAB9AMEN1ALPG | |
| SCHEMBL25879067 | 0.72 | KMT2A (0.55) | MAPTKDM4ERAB9AMEN1ALPG | |
| SCHEMBL25876099 | 0.72 | MEN1 (0.55) | MAPTKDM4ERAB9AMEN1ALPG | |
| SCHEMBL25883121 | 0.72 | RAB9A (0.55) | MAPTKDM4ERAB9AMEN1ALPG | |
| SCHEMBL25876445 | 0.72 | RAB9A (0.55) | MAPTKDM4ERAB9AMEN1ALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215526-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2023-07-26 | — | — | EP | disclosed |