Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MLYCD | O95822 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3278792 | 0.80 | HSD11B1 (0.48) | MLYCDALOX5TRPM8ALDH1A1HPGD | |
| SCHEMBL25890673 | 0.77 | POLB (0.41) | POLBMLYCDTRPM8ALDH1A1HPGD | |
| SCHEMBL9877218 | 0.75 | POLB (0.58) | POLBALDH1A1LMNACYP3A4CYP2C9 | |
| SCHEMBL154606 | 0.72 | TRPM8 (0.53) | MLYCDTRPM8ALDH1A1HPGDPGR | |
| SCHEMBL3280418 | 0.72 | POLB (0.55) | POLBALDH1A1HPGDHSD11B1LMNA | |
| SCHEMBL11262719 | 0.71 | POLB (0.53) | POLBALDH1A1HPGDHSD11B1LMNA | |
| SCHEMBL6831416 | 0.71 | NOD2 (0.48) | MLYCDTRPM8ALDH1A1HPGDPGR | |
| SCHEMBL458409 | 0.70 | NPSR1 (0.59) | MLYCDTRPM8ALDH1A1HPGDPGR | |
| SCHEMBL11122024 | 0.70 | POLB (0.56) | POLBALDH1A1HPGDHSD11B1LMNA | |
| SCHEMBL13571402 | 0.70 | MLYCD (0.53) | POLBMLYCDTRPM8ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3877372-B1 | ENANTIOSELECTIVE REDUCTION OF OXIME-DERIVATIVES INVOLVING IRIDIUM BASED CATALYSTS | SYNGENTA CROP PROTECTION AG (CH) | 2023-08-02 | — | — | EP | disclosed |