Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | MIF | P14174 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2589100 | 1.00 | L3MBTL1 (0.68) | L3MBTL1HPGDALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL7270862 | 0.89 | ALDH1A1 (0.70) | L3MBTL1HPGDALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL696955 | 0.89 | ALDH1A1 (0.70) | L3MBTL1HPGDALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL6306459 | 0.89 | ALDH1A1 (0.70) | L3MBTL1HPGDALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL395524 | 0.85 | L3MBTL1 (0.92) | L3MBTL1HPGDALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL29757867 | 0.85 | L3MBTL1 (0.92) | L3MBTL1HPGDALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL5398653 | 0.85 | L3MBTL1 (0.92) | L3MBTL1HPGDALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL30043171 | 0.85 | L3MBTL1 (0.92) | L3MBTL1HPGDALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL1204352 | 0.85 | L3MBTL1 (0.92) | L3MBTL1HPGDALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL2217559 | 0.81 | HPGD (1.00) | L3MBTL1HPGDALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9520574-B2 | Electroluminescent devices based on phosphorescent iridium and related group VIII metal multicyclic compounds | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2016-12-13 | — | — | US | disclosed |
| US-20130082248-A1 | ELECTROLUMINESCENT DEVICES BASED ON PHOSPHORESCENT IRIDIUM AND RELATED GROUP VIII METAL MULTICYCLIC COMPOUNDS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2013-04-04 | — | — | US | disclosed |
| EP-2564446-A1 | ELECTROLUMINESCENT DEVICES BASED ON PHOSPHORESCENT IRIDIUM AND RELATED GROUP VIII METAL MULTICYCLIC COMPOUNDS | Commonwealth Scientific and Industrial Research Organisation (AU) | 2013-03-06 | — | — | EP | disclosed |
| EP-2398794-A1 | HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2011-12-28 | — | — | EP | disclosed |
| WO-2011134013-A1 | ELECTROLUMINESCENT DEVICES BASED ON PHOSPHORESCENT IRIDIUM AND RELATED GROUP VIII METAL MULTICYCLIC COMPOUNDS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2011-11-03 | — | — | WO | disclosed |
| WO-2010096302-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-08-26 | — | — | WO | disclosed |
| EP-0399422-A1 | Benzocycloalkane derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1990-11-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130082248-A1 | ELECTROLUMINESCENT DEVICES BASED ON PHOSPHORESCENT IRIDIUM AND RELATED GROUP VIII METAL MULTICYCLIC COMPOUNDS | ICOSLG, ETV6, ROS1 | L3MBTL1 2005/4885HPGD 3462/4885ALDH1A1 798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.