Sugi Predict

Sugi Predict / Compounds / SCHEMBL395524

SCHEMBL395524

SCHEMBL395524

ON=C1CCCc2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 4/20 0.92
▸ HPGD P15428 3/20 0.92
▸ LMNA P02545 2/20 0.52
▸ HSD17B10 Q99714 1/20 0.52
▸ G6PC1 P35575 1/20 0.51
▸ ALDH1A1 P00352 4/20 0.51
▸ CYP2A6 P11509 1/20 0.50
▸ MAOA P21397 1/20 0.50
▸ MAOB P27338 1/20 0.50
▸ MAPT P10636 3/20 0.49
▸ MEN1 O00255 2/20 0.49
▸ KMT2A Q03164 2/20 0.49
▸ GAA P10253 2/20 0.49
▸ NPC1 O15118 1/20 0.49
▸ RAB9A P51151 1/20 0.49
▸ SMN1; SMN2 Q16637 1/20 0.49
▸ CYP1A2 P05177 1/20 0.48
▸ CYP2C19 P33261 1/20 0.48
▸ PLA2G1B P04054 1/20 0.48
▸ ATG4B Q9Y4P1 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30043171 1.00 L3MBTL1 (0.92) L3MBTL1HPGDLMNAHSD17B10G6PC1
SCHEMBL5398653 1.00 L3MBTL1 (0.92) L3MBTL1HPGDLMNAHSD17B10G6PC1
SCHEMBL1204352 1.00 L3MBTL1 (0.92) L3MBTL1HPGDLMNAHSD17B10G6PC1
SCHEMBL29757867 1.00 L3MBTL1 (0.92) L3MBTL1HPGDLMNAHSD17B10G6PC1
SCHEMBL30528190 0.96 HPGD (1.00) L3MBTL1HPGDLMNAHSD17B10G6PC1
SCHEMBL2217555 0.96 HPGD (1.00) L3MBTL1HPGDLMNAHSD17B10G6PC1
SCHEMBL2217559 0.96 HPGD (1.00) L3MBTL1HPGDLMNAHSD17B10G6PC1
SCHEMBL17988339 0.94 HPGD (0.96) L3MBTL1HPGDLMNAHSD17B10G6PC1
Acetic Acid SCHEMBL28410022 0.89 L3MBTL1 (0.74) L3MBTL1HPGDLMNAG6PC1ALDH1A1
SCHEMBL2733083 0.87 HPGD (0.77) L3MBTL1HPGDLMNAHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 236 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112500346-B Synthesis method of 5, 6-dihydrobenzo [ c ] acridine 湖南工程学院 2022-03-01 — — CN claimed
CN-109232309-A A kind of processing method improving 1-tetralone oxime output capacity and purifying 安徽绩溪县徽煌化工有限公司 2019-01-18 — — CN claimed
CN-102675123-A Resolving and racemization method for 1-amino-1,2,3,4-tetrahydronaphthalene SHANGHAI LANGTZE BIOMEDICAL TECHNOLOGY CO LTD 2012-09-19 — — CN claimed
EP-0051805-B1 PROCESS FOR THE PREPARATION OF AROMATIC AMINES HOECHST AKTIENGESELLSCHAFT (DE) 1984-01-18 — — EP claimed
US-4375561-A Process for the preparation of aromatic amines HOECHST AKTIENGESELLSCHAFT (DE) 1983-03-01 — — US claimed
US-20250282792-A1 GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO NEUROCRINE BIOSCIENCES, INC. 2025-09-11 — — US disclosed
EP-4019607-B1 ELECTROCHROMIC COMPOUNDS AND OPTICAL ARTICLES CONTAINING THEM ESSILOR INT (FR) 2024-05-15 — — EP disclosed
CN-117720433-A Preparation method and application of oxime carbonate compound 河南农业大学 2024-03-19 — — CN disclosed
US-20240052235-A1 ELECTROCHROMIC COMPOUNDS AND OPTICAL ARTICLES CONTAINING THEM ESSILOR INTERNATIONAL (FR) 2024-02-15 — — US disclosed
CN-116783168-A Electrochromic compounds and optical articles comprising the same 依视路国际公司 2023-09-19 — — CN disclosed
US-11713324-B2 Gonadotropin-releasing hormone receptor antagonists and methods relating thereto NEUROCRINE BIOSCIENCES, INC. (US) 2023-08-01 — — US disclosed
CN-114394913-B Synthetic method of oxime ether derivative 山东农业大学 2023-02-03 — — CN disclosed
EP-0220845-A1 Heterocyclic compounds and their preparation and use A/S FERROSAN (DK) 1987-05-06 — — EP disclosed
US-4375561-A Process for the preparation of aromatic amines HOECHST AKTIENGESELLSCHAFT (DE) 1983-03-01 — — US disclosed
US-4340595-A ADRENERGIC BLOCKING AGENTS BASF AKTIENGESELLSCHAFT (DE) 1982-07-20 — — US disclosed
EP-0011747-B1 AMINOPROPANOL DERIVATIVES OF 6-HYDROXY-2,3,4,5-TETRAHYDRO-1H-1-BENZAZEPIN-2-ONES, PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM BASF Aktiengesellschaft (DE) 1982-05-19 — — EP disclosed
EP-0011747-A1 Aminopropanol derivatives of 6-hydroxy-2,3,4,5-tetrahydro-1H-1-benzazepin-2-ones, process for their preparation, and pharmaceutical compositions containing them BASF Aktiengesellschaft (DE) 1980-06-11 — — EP disclosed
US-4062856-A ANIMAL GROWTH REGULATOR, HERBICIDE AMERICAN CYANAMID CO. (US) 1977-12-13 — — US disclosed
US-4005140-A ANIMAL GROWTH REGULATORS, HERBICIDES AMERICAN CYANAMID COMPANY (US) 1977-01-25 — — US disclosed
US-3953506-A ANIMAL GROWTH REGULATORS, HERBICIDES AMERICAN CYANAMID COMPANY (US) 1976-04-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250282792-A1 GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO GNRHR, GHRHR, LHCGR L3MBTL1 2538/4885HPGD 1199/4885LMNA 2727/4885
US-11713324-B2 Gonadotropin-releasing hormone receptor antagonists and methods relating thereto GNRHR, GHRHR, LHCGR L3MBTL1 2538/4885HPGD 1199/4885LMNA 2727/4885
US-20240052235-A1 ELECTROCHROMIC COMPOUNDS AND OPTICAL ARTICLES CONTAINING THEM EYA3, LAGE3, CDKL5 L3MBTL1 4640/4885HPGD 1734/4885LMNA 1134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.