Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.92 |
| ▸ | HPGD | P15428 | 3/20 | 0.92 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.48 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL395524 | 1.00 | L3MBTL1 (0.92) | L3MBTL1HPGDLMNAHSD17B10G6PC1 | |
| SCHEMBL30043171 | 1.00 | L3MBTL1 (0.92) | L3MBTL1HPGDLMNAHSD17B10G6PC1 | |
| SCHEMBL1204352 | 1.00 | L3MBTL1 (0.92) | L3MBTL1HPGDLMNAHSD17B10G6PC1 | |
| SCHEMBL29757867 | 1.00 | L3MBTL1 (0.92) | L3MBTL1HPGDLMNAHSD17B10G6PC1 | |
| SCHEMBL30528190 | 0.96 | HPGD (1.00) | L3MBTL1HPGDLMNAHSD17B10G6PC1 | |
| SCHEMBL2217555 | 0.96 | HPGD (1.00) | L3MBTL1HPGDLMNAHSD17B10G6PC1 | |
| SCHEMBL2217559 | 0.96 | HPGD (1.00) | L3MBTL1HPGDLMNAHSD17B10G6PC1 | |
| SCHEMBL17988339 | 0.94 | HPGD (0.96) | L3MBTL1HPGDLMNAHSD17B10G6PC1 | |
| Acetic Acid SCHEMBL28410022 | 0.89 | L3MBTL1 (0.74) | L3MBTL1HPGDLMNAG6PC1ALDH1A1 | |
| SCHEMBL2733083 | 0.87 | HPGD (0.77) | L3MBTL1HPGDLMNAHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159463-A1 | BENZONITRIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI ZHONGZE THERAPEUTICS, CO. LTD. (CN) | 2023-05-25 | — | — | US | disclosed |
| US-10011559-B2 | Preparation of chiral amides and amines | SUNOVION PHARMACEUTICALS INC. (US) | 2018-07-03 | — | — | US | disclosed |
| US-20180016224-A1 | PREPARATION OF CHIRAL AMIDES AND AMINES | SUNOVION PHARMACEUTICALS INC. | 2018-01-18 | — | — | US | disclosed |
| EP-2816024-B1 | Chiral amines | SUNOVION PHARMACEUTICALS INC (US) | 2017-08-02 | — | — | EP | disclosed |
| EP-2701512-B1 | ALDOSTERONE SYNTHASE INHIBITORS | MERCK SHARP & DOHME (US) | 2017-04-05 | — | — | EP | disclosed |
| US-20160016891-A1 | PREPARATION OF CHIRAL AMIDES AND AMINES | SUNOVION PHARMACEUTICALS INC. | 2016-01-21 | — | — | US | disclosed |
| US-9073929-B2 | Aldosterone synthase inhibitors | ELEXOPHARM GMBH (DE) | 2015-07-07 | — | — | US | disclosed |
| US-20140057990-A1 | PREPARATION OF CHIRAL AMIDES AND AMINES | SUNOVION PHARMACEUTICALS INC. (US) | 2014-02-27 | — | — | US | disclosed |
| US-20140045819-A1 | ALDOSTERONE SYNTHASE INHIBITORS | ELEXOPHARM GMBH (DE) | 2014-02-13 | — | — | US | disclosed |
| US-8524950-B2 | Preparation of chiral amides and amines | SUNOVION PHARMACEUTICALS INC. (US) | 2013-09-03 | — | — | US | disclosed |
| US-20120095106-A1 | PREPARATION OF CHIRAL AMIDES AND AMINES | SUNOVION PHARMACEUTICALS INC. (US) | 2012-04-19 | — | — | US | disclosed |
| US-7169773-B2 | Compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2007-01-30 | — | — | US | disclosed |
| US-7169773-B2 | Compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2007-01-30 | — | — | US | disclosed |
| US-7169773-B2 | Compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2007-01-30 | — | — | US | disclosed |
| US-20060003991-A1 | Compounds | SZEWCZYK JERZY R | 2006-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10011559-B2 | Preparation of chiral amides and amines | PNMT, ALKBH5, ALKBH2 | L3MBTL1 4178/4885HPGD 582/4885LMNA 1993/4885 |
| US-20180016224-A1 | PREPARATION OF CHIRAL AMIDES AND AMINES | PNMT, ALKBH2, ALKBH5 | L3MBTL1 4177/4885HPGD 630/4885LMNA 1904/4885 |
| US-20160016891-A1 | PREPARATION OF CHIRAL AMIDES AND AMINES | PNMT, ALKBH5, ALKBH2 | L3MBTL1 4178/4885HPGD 582/4885LMNA 1993/4885 |
| US-20230159463-A1 | BENZONITRIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | HDAC11, HDAC1, HDAC6 | L3MBTL1 2681/4885HPGD 406/4885LMNA 2388/4885 |
| US-20060003991-A1 | Compounds | SLC10A1, SLC10A2, ABCB11 | L3MBTL1 4845/4885HPGD 817/4885LMNA 4142/4885 |
| US-20120095106-A1 | PREPARATION OF CHIRAL AMIDES AND AMINES | PNMT, ALKBH5, ALKBH2 | L3MBTL1 4178/4885HPGD 582/4885LMNA 1993/4885 |
| US-20140057990-A1 | PREPARATION OF CHIRAL AMIDES AND AMINES | PNMT, ALKBH5, ALKBH2 | L3MBTL1 4178/4885HPGD 582/4885LMNA 1993/4885 |
| US-20140045819-A1 | ALDOSTERONE SYNTHASE INHIBITORS | CYP21A2, CYP17A1, HSD11B1 | L3MBTL1 4693/4885HPGD 220/4885LMNA 2434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.