Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.36 |
| ▸ | PPARA | Q07869 | 5/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20244408 | 0.80 | PPARG (0.43) | PPARGPPARAHTR1DLMNATYR | |
| SCHEMBL27252485 | 0.78 | TYR (0.39) | PPARGPPARAHTR1DLMNAACHE | |
| SCHEMBL4107540 | 0.77 | LMNA (0.47) | XDHGABRA1GABRB2LMNAACHE | |
| SCHEMBL12802029 | 0.77 | CNR2 (0.40) | PPARGPPARAXDHDHFRGABRA1 | |
| SCHEMBL17049796 | 0.77 | PPARG (0.39) | PPARGPPARAHTR1DLMNATRPA1 | |
| SCHEMBL873331 | 0.77 | LMNA (0.42) | XDHGABRA1GABRB2LMNAACHE | |
| SCHEMBL24751622 | 0.77 | PPARG (0.40) | PPARGPPARAHTR1DLMNAACHE | |
| SCHEMBL9028982 | 0.76 | XDH (0.49) | PPARGXDHGABRA1GABRB2TYR | |
| SCHEMBL9816379 | 0.76 | GABRA1 (0.59) | PPARGXDHGABRA1GABRB2LMNA | |
| SCHEMBL21262991 | 0.76 | ALDH1A1 (0.43) | XDHGABRA1GABRB2HTR1DLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141323-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-07-27 | — | — | WO | disclosed |