Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23934357 | 0.83 | ALDH1A1 (0.37) | MAPTLMNAALDH1A1POLBTHRB | |
| SCHEMBL24160213 | 0.83 | THRB (0.38) | MAPTLMNAALDH1A1POLBTHRB | |
| SCHEMBL23129062 | 0.83 | MAPT (0.40) | MAPTLMNAALDH1A1POLBTHRB | |
| SCHEMBL22354687 | 0.83 | MEN1 (0.37) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL23739877 | 0.83 | MAPT (0.38) | MAPTLMNAALDH1A1POLBTHRB | |
| SCHEMBL13258696 | 0.83 | THRB (0.38) | MAPTLMNAALDH1A1POLBTHRB | |
| SCHEMBL23739470 | 0.82 | LMNA (0.36) | MAPTLMNAALDH1A1POLBTHRB | |
| SCHEMBL26289667 | 0.82 | KMT2A (0.37) | MAPTLMNAALDH1A1POLBTHRB | |
| SCHEMBL22667455 | 0.81 | LMNA (0.35) | MAPTLMNAMEN1KMT2A | |
| SCHEMBL19986318 | 0.81 | MEN1 (0.35) | MAPTLMNAALDH1A1POLBTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023115149-A1 | BIFUNCTIONAL SULPHONAMIDE COMPOUNDS | Anaxis Pharma Pty Ltd (AU) | 2023-06-29 | — | — | WO | disclosed |