Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.37 |
| ▸ | HPD | P32754 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31160230 | 0.87 | AKR1A1 (0.32) | CYP19A1HPD | |
| SCHEMBL26831181 | 0.82 | CYP19A1 (0.34) | CYP19A1MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL31287367 | 0.82 | CYP19A1 (0.37) | CYP19A1MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL29258438 | 0.78 | VCAM1 (0.39) | CYP19A1MEN1KMT2AACACBGRIN2D | |
| SCHEMBL18398574 | 0.78 | MAPT (0.33) | HPDMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL1675629 | 0.78 | MAPT (0.43) | MAPTMEN1ALDH1A1KMT2AMAPK1 | |
| SCHEMBL26834351 | 0.77 | GRIN2D (0.43) | CYP19A1HPDMAPTMEN1ALDH1A1 | |
| SCHEMBL1358844 | 0.76 | TDP1 (0.39) | MAPTMEN1ALDH1A1KMT2AMAPK1 | |
| SCHEMBL31160144 | 0.75 | PDE5A (0.40) | CYP19A1ALDH1A1GAA | |
| SCHEMBL26834411 | 0.75 | CYP19A1 (0.33) | CYP19A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240067648-A1 | N-OXIDE INHIBITORS OF NLRP3 INFLAMMASOME | BioAge Labs, Inc. | 2024-02-29 | — | — | US | disclosed |
| US-11787805-B2 | N-oxide inhibitors of NLRP3 inflammasome | BioAge Labs, Inc. (US) | 2023-10-17 | — | — | US | disclosed |
| US-20230242528-A1 | N-OXIDE INHIBITORS OF NLRP3 INFLAMMASOME | BioAge Labs, Inc. | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242528-A1 | N-OXIDE INHIBITORS OF NLRP3 INFLAMMASOME | NLRP3, NOD1, CASP1 | CYP19A1 4086/4885HPD 2361/4885MAPT 940/4885 |
| US-20240067648-A1 | N-OXIDE INHIBITORS OF NLRP3 INFLAMMASOME | NLRP3, NOD1, CASP1 | CYP19A1 4086/4885HPD 2361/4885MAPT 940/4885 |
| US-11787805-B2 | N-oxide inhibitors of NLRP3 inflammasome | NLRP3, NOD1, CASP1 | CYP19A1 4086/4885HPD 2361/4885MAPT 940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.