Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL731013 | 0.89 | LMNA (0.50) | LMNAPOLBKMT2ACREBBPMEN1 | |
| SCHEMBL732996 | 0.84 | TSHR (0.50) | LMNAKMT2ACREBBPNCOA1NCOA3 | |
| SCHEMBL20763421 | 0.84 | KMT2A (0.48) | LMNAPOLBKMT2AMEN1GAA | |
| SCHEMBL9276266 | 0.83 | LMNA (0.51) | LMNAPOLBKMT2ACREBBPGAA | |
| SCHEMBL25902206 | 0.82 | HTT (0.52) | LMNAHTTRORCPOLBKMT2A | |
| SCHEMBL8336289 | 0.82 | CA1 (0.52) | LMNAHTTPOLBKMT2AMEN1 | |
| SCHEMBL1398536 | 0.81 | MEN1 (0.59) | LMNARORCPOLBKMT2ACREBBP | |
| SCHEMBL6293600 | 0.79 | LMNA (0.55) | LMNAHTTPOLBKMT2AMEN1 | |
| Methylamine SCHEMBL5152509 | 0.79 | POLB (0.56) | LMNAHTTRORCPOLBKMT2A | |
| SCHEMBL16930354 | 0.78 | ALDH1A1 (0.53) | LMNAHTTRORCPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240067648-A1 | N-OXIDE INHIBITORS OF NLRP3 INFLAMMASOME | BioAge Labs, Inc. | 2024-02-29 | — | — | US | disclosed |
| US-20240067648-A1 | N-OXIDE INHIBITORS OF NLRP3 INFLAMMASOME | BioAge Labs, Inc. | 2024-02-29 | — | — | US | disclosed |
| US-11787805-B2 | N-oxide inhibitors of NLRP3 inflammasome | BioAge Labs, Inc. (US) | 2023-10-17 | — | — | US | disclosed |
| US-11787805-B2 | N-oxide inhibitors of NLRP3 inflammasome | BioAge Labs, Inc. (US) | 2023-10-17 | — | — | US | disclosed |
| US-20230242528-A1 | N-OXIDE INHIBITORS OF NLRP3 INFLAMMASOME | BioAge Labs, Inc. | 2023-08-03 | — | — | US | disclosed |
| US-20230242528-A1 | N-OXIDE INHIBITORS OF NLRP3 INFLAMMASOME | BioAge Labs, Inc. | 2023-08-03 | — | — | US | disclosed |
| WO-2023147468-A1 | N-OXIDE INHIBITORS OF NLRP3 INFLAMMASOME | BioAge Labs, Inc. (US) | 2023-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242528-A1 | N-OXIDE INHIBITORS OF NLRP3 INFLAMMASOME | NLRP3, NOD1, CASP1 | LMNA 407/4885HTT 1393/4885RORC 634/4885 |
| US-20240067648-A1 | N-OXIDE INHIBITORS OF NLRP3 INFLAMMASOME | NLRP3, NOD1, CASP1 | LMNA 407/4885HTT 1393/4885RORC 634/4885 |
| US-11787805-B2 | N-oxide inhibitors of NLRP3 inflammasome | NLRP3, NOD1, CASP1 | LMNA 407/4885HTT 1393/4885RORC 634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.