SCHEMBL2590500

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2581632	0.96	SIGMAR1 (0.37)	BCL9CTNNB1HRH3ALDH1A1KEAP1
	SCHEMBL2492107	0.87	HTR1A (0.42)	BCL9CTNNB1HRH3ALDH1A1HTR1A
	SCHEMBL2489928	0.87	HTR1A (0.41)	BCL9CTNNB1HRH3ALDH1A1HTR1A
	SCHEMBL2460946	0.86	POLB (0.43)	ALDH1A1KDM4ETDP1
	SCHEMBL2493820	0.86	BCHE (0.40)	BCL9CTNNB1HRH3ALDH1A1HTR1A
	SCHEMBL2461002	0.85	POLB (0.48)	ALDH1A1MAPK1CNR2KDM4ETDP1
	SCHEMBL2492036	0.81	HTR1A (0.37)	BCL9CTNNB1HRH3ALDH1A1HTR1A
	SCHEMBL2493992	0.80	HTR1A (0.44)	BCL9CTNNB1HRH3ALDH1A1HTR1A
	SCHEMBL2492005	0.80	HRH3 (0.43)	HRH3HTR1AHTR7
	SCHEMBL2496305	0.80	HTR1A (0.46)	BCL9CTNNB1HRH3ALDH1A1HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.