SCHEMBL2581632

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2590500	0.96	BCL9 (0.37)	ALDH1A1KEAP1NFE2L2CNR1CNR2
	SCHEMBL2493820	0.88	BCHE (0.40)	SIGMAR1ALDH1A1CNR1CNR2KDM4E
	SCHEMBL2461002	0.86	POLB (0.48)	ALDH1A1CNR2KDM4EPOLBKDM5B
	SCHEMBL2492107	0.85	HTR1A (0.42)	SIGMAR1ALDH1A1KDM4EBCL9CTNNB1
	SCHEMBL2489928	0.85	HTR1A (0.41)	SIGMAR1ALDH1A1KDM4EBCL9CTNNB1
	SCHEMBL2460946	0.85	POLB (0.43)	ALDH1A1KDM4EPOLB
	SCHEMBL2590555	0.80	POLB (0.44)	ALDH1A1KDM4EPOLBKDM5B
	SCHEMBL2581807	0.80	CHRM1 (0.45)	KEAP1NFE2L2CNR1CNR2
	SCHEMBL12160572	0.80	KDM4E (0.37)	ALDH1A1KDM4EPOLB
	SCHEMBL2489540	0.80	RAB9A (0.45)	ALDH1A1KDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.