SCHEMBL25906240

SCHEMBL25906240

C=C(C)C(=O)Oc1ccc2c(oc3c(OC)c(OC)ccc32)c1OC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.50
KDM4E B2RXH2 5/20 0.50
MAOA P21397 4/20 0.46
MAOB P27338 3/20 0.45
CA9 Q16790 2/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA7 P43166 1/20 0.43
CA13 Q8N1Q1 1/20 0.43
HPGD P15428 3/20 0.43
HSD17B10 Q99714 3/20 0.43
MEN1 O00255 1/20 0.43
MAPK1 P28482 1/20 0.43
KMT2A Q03164 1/20 0.43
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C19 P33261 1/20 0.41
NCOA1 Q15788 1/20 0.41
NCOA3 Q9Y6Q9 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25874472 0.97 MAOA (0.47) ALDH1A1KDM4EMAOAMAOBCA9
SCHEMBL25874215 0.90 KDM4E (0.47) ALDH1A1KDM4EMAOAMAOBCA9
SCHEMBL25873940 0.89 MAOA (0.44) ALDH1A1KDM4EMAOAMAOBCA9
SCHEMBL25874546 0.87 MAOA (0.40) ALDH1A1KDM4EMAOAMAOBCA9
SCHEMBL25874477 0.86 MAOA (0.40) ALDH1A1KDM4EMAOAMAOBCA9
SCHEMBL25876144 0.84 ADORA3 (0.41) ALDH1A1KDM4EMAOAMAOBCA9
SCHEMBL25873787 0.83 TUBB4A (0.42) ALDH1A1KDM4EMAOAMAOBCA9
SCHEMBL25906136 0.82 HPGD (0.49) ALDH1A1KDM4EMAOAMAOBHPGD
SCHEMBL25874891 0.80 ALDH1A1 (0.35) ALDH1A1KDM4EMAOAMAOBHPGD
SCHEMBL25874210 0.78 GBA1 (0.49) ALDH1A1KDM4EMAOAMAOBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023134595-A1 POLYMERIZABLE COMPOUND, COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed