SCHEMBL25907720

SCHEMBL25907720

CCOc1cc(C)c(CS(=O)(=O)C2=NOC(C)(C)C2)cc1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.38
TDP1 Q9NUW8 1/20 0.36
HTT P42858 7/20 0.36
TSHR P16473 6/20 0.36
LMNA P02545 3/20 0.36
MAPT P10636 3/20 0.36
GAA P10253 1/20 0.36
ALPL P05186 1/20 0.33
ALDH1A1 P00352 5/20 0.32
SMN1; SMN2 Q16637 3/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
SGPL1 O95470 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fenoxasulfone SCHEMBL29489596 0.80 SMN1; SMN2 (0.35) KDM4EHTTTSHRLMNAMAPT
SCHEMBL28706810 0.80 ALDH1A1 (0.34) KDM4EHTTTSHRLMNAMAPT
SCHEMBL14983762 0.75 SOD1 (0.36)
SCHEMBL5296529 0.69 PSEN1 (0.47) HTTMAPTALDH1A1
SCHEMBL14320063 0.69 MAPT (0.32) HTTLMNAMAPTALDH1A1MEN1
SCHEMBL14311721 0.69
SCHEMBL30619991 0.68 MAPT (0.32) TSHRMAPTALDH1A1SMN1; SMN2KMT2A
SCHEMBL29110170 0.68 MAPT (0.32) TSHRMAPTALDH1A1SMN1; SMN2KMT2A
SCHEMBL22911574 0.68
SCHEMBL24351538 0.68 KDM4E (0.45) KDM4ETDP1HTTTSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230234947-A1 PROCESS AND INTERMEDIATES FOR THE PREPARATION OF PYROXASULFONE, FENOXASULFONE AND VARIOUS SULFONE ANALOGS OF 5,5-DIMETHYL-4H-1,2-OXAZOLE ADAMA AGAN LTD. (IL) 2023-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230234947-A1 PROCESS AND INTERMEDIATES FOR THE PREPARATION OF PYROXASULFONE, FENOXASULFONE AND VARIOUS SULFONE ANALOGS OF 5,5-DIMETHYL-4H-1,2-OXAZOLE TST, TXN2, PRDX1 KDM4E 1512/4885TDP1 975/4885HTT 3649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.