SCHEMBL25909558

SCHEMBL25909558

CCC(CC)O[Si](OC(CC)CC)(c1ccccc1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.35
HTT P42858 1/20 0.34
TP53 P04637 1/20 0.32
MCHR1 Q99705 1/20 0.32
PIN1 Q13526 1/20 0.32
PRNP P04156 1/20 0.31
TRPA1 O75762 1/20 0.31
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL427067 0.81 MAPT (0.35) LMNAHTTTP53MCHR1PIN1
SCHEMBL14369907 0.80 LMNA (0.35) LMNAHTTTDP1
SCHEMBL3164541 0.78 ADRA2A (0.40) LMNAHTTTDP1
SCHEMBL5359631 0.78 TDP1 (0.33) LMNAHTTTDP1
SCHEMBL10709298 0.78 LMNA (0.32) LMNA
SCHEMBL106516 0.75 TSHR (0.36) LMNAESR1ESR2TDP1
SCHEMBL705119 0.73 ESR1 (0.37) LMNAESR1ESR2TDP1
SCHEMBL25909547 0.71 HTR2A (0.39) LMNATDP1
SCHEMBL25909561 0.71 IDO1 (0.44) LMNATDP1
SCHEMBL34937 0.70 LTA4H (0.37) HTTTP53PIN1ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230241597-A1 PLATFORM FOR THE RECOVERY OF TRANSITION METAL CATALYSTS TEXAS TECH UNIVERSITY SYSTEM 2023-08-03 US disclosed