SCHEMBL25909561

SCHEMBL25909561

CC(O[Si](OC(C)c1ccc(Cl)cc1)(c1ccccc1)c1ccccc1)c1ccc(Cl)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.44
TDO2 P48775 3/20 0.44
ADRB2 P07550 1/20 0.39
CYP2D6 P10635 2/20 0.38
CYP2C19 P33261 2/20 0.38
TSHR P16473 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
KCNH3 Q9ULD8 1/20 0.36
LMNA P02545 3/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
GMNN O75496 1/20 0.36
MAPT P10636 1/20 0.36
PMP22 Q01453 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
KDM4E B2RXH2 2/20 0.36
MAPK1 P28482 1/20 0.36
CHRM2 P08172 1/20 0.36
HTR1A P08908 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3164541 0.87 ADRA2A (0.40) CYP2D6TDP1LMNAMEN1KMT2A
SCHEMBL25909547 0.82 HTR2A (0.39) CYP2D6TDP1LMNAMEN1KMT2A
SCHEMBL106516 0.72 TSHR (0.36) TSHRTDP1LMNAMAPTNPSR1
SCHEMBL25909558 0.71 LMNA (0.35) TDP1LMNA
SCHEMBL11526330 0.71 ADRA2A (0.40) CYP2D6TDP1LMNAKDM4EADRA2A
SCHEMBL705119 0.70 ESR1 (0.37) TSHRTDP1LMNAMAPTNPSR1
SCHEMBL25948551 0.69 ADRA2A (0.39) CYP2D6LMNAKDM4EADRA2A
SCHEMBL8157398 0.68 SLC6A4 (0.53) IDO1TDO2CYP2D6CYP2C19NPSR1
SCHEMBL29178938 0.68 ESR1 (0.42) IDO1TDO2CYP2D6CYP2C19TDP1
SCHEMBL10690940 0.68 IDO1 (0.46) IDO1TDO2ADRB2CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230241597-A1 PLATFORM FOR THE RECOVERY OF TRANSITION METAL CATALYSTS TEXAS TECH UNIVERSITY SYSTEM 2023-08-03 US disclosed