Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL706709 | 0.71 | CALM1 (0.35) | MAOBLMNATSHRALDH1A1TDP1 | |
| SCHEMBL31216314 | 0.70 | CYP1A2 (0.47) | KDM1AMAOAMAOBSIGMAR1ATM | |
| SCHEMBL60979 | 0.69 | CTSS (0.54) | MAOAMAOBSIGMAR1EPHX2 | |
| SCHEMBL2456244 | 0.69 | KDM1A (0.41) | KDM1AMAOAMAOBSIGMAR1ATM | |
| SCHEMBL10318703 | 0.69 | EPHX2 (0.38) | KDM1AMAOAMAOBSIGMAR1EPHX2 | |
| SCHEMBL6570842 | 0.68 | CYP2D6 (0.47) | KDM1AMAOAMAOBSIGMAR1L3MBTL1 | |
| SCHEMBL8217474 | 0.68 | EPHX2 (0.37) | KDM1AMAOAMAOBSIGMAR1ATM | |
| SCHEMBL1733071 | 0.67 | CEL (0.51) | KDM1AMAOAMAOBSIGMAR1LMNA | |
| SCHEMBL705394 | 0.67 | CTSS (0.56) | MAOAMAOB | |
| SCHEMBL7419921 | 0.67 | SLC18A3 (0.60) | KDM1AMAOAMAOBSIGMAR1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230241597-A1 | PLATFORM FOR THE RECOVERY OF TRANSITION METAL CATALYSTS | TEXAS TECH UNIVERSITY SYSTEM | 2023-08-03 | — | — | US | disclosed |
| CN-111393466-A | Gem disilicon compound, preparation method and application thereof | 南开大学 | 2020-07-10 | — | — | CN | disclosed |