SCHEMBL25912779

SCHEMBL25912779

CC(C)Nc1ccc(-c2nnc(-c3ncccn3)nn2)nc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 5/20 0.41
LMNA P02545 4/20 0.41
L3MBTL1 Q9Y468 3/20 0.41
MAPT P10636 3/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
MITF O75030 1/20 0.41
TP53 P04637 1/20 0.39
TDP1 Q9NUW8 3/20 0.36
CYP3A4 P08684 2/20 0.36
RECQL P46063 2/20 0.36
ALDH1A1 P00352 1/20 0.36
THRB P10828 1/20 0.36
ALOX15 P16050 1/20 0.36
TSHR P16473 1/20 0.36
ALOX12 P18054 1/20 0.36
ATM Q13315 1/20 0.36
HSD17B10 Q99714 1/20 0.36
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
CYP1A2 P05177 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13860906 0.74 TYRO3 (0.41) CYP3A4KCNH2CYP2D6
SCHEMBL27405407 0.73 TDP1 (0.50) LMNAL3MBTL1TDP1CYP3A4RECQL
SCHEMBL25912786 0.71 P4HTM (0.41) TRPM8L3MBTL1TP53CYP3A4RECQL
SCHEMBL13736761 0.71 RAB9A (0.54) LMNAMAPTSMN1; SMN2TP53ALDH1A1
SCHEMBL22477301 0.71 PTPN1 (0.43) MAPTSMN1; SMN2TP53HSD17B10HIF1A
SCHEMBL23636379 0.71 RAB9A (0.39) LMNAMAPTSMN1; SMN2TP53ALDH1A1
SCHEMBL18653596 0.70 PTPN1 (0.42) MAPTSMN1; SMN2HIF1A
SCHEMBL19010907 0.69 NPC1 (0.46) TRPM8L3MBTL1MAPTSMN1; SMN2TP53
SCHEMBL4111367 0.69 TP53 (0.51) L3MBTL1MAPTSMN1; SMN2TP53ALDH1A1
SCHEMBL13830642 0.68 RAB9A (0.37) LMNAMAPTSMN1; SMN2TP53ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230218766-A1 SUGAR COMPOUND HAVING POLYETHYLENE GLYCOL CHAIN, AND PRECURSOR OF ANTIBODY-DRUG COMPLEX THE NOGUCHI INSTITUTE (JP) 2023-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230218766-A1 SUGAR COMPOUND HAVING POLYETHYLENE GLYCOL CHAIN, AND PRECURSOR OF ANTIBODY-DRUG COMPLEX FCGRT, HBZ, FUT4 TRPM8 4803/4885LMNA 3887/4885L3MBTL1 3797/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.