Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | MEP1B | Q16820 | 3/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11893184 | 0.86 | PRSS1 (0.48) | SLC7A5GRM2LOXL2F2F10 | |
| SCHEMBL7385091 | 0.82 | LOXL2 (0.55) | SLC7A5LOXL2ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL7350811 | 0.81 | SMN1; SMN2 (0.45) | SLC7A5RAB9ASMN1; SMN2HDAC1HDAC3 | |
| SCHEMBL11891918 | 0.79 | SLC7A5 (0.43) | SLC7A5GRM2LOXL2RAB9AHDAC1 | |
| SCHEMBL19256701 | 0.79 | SLC7A5 (0.43) | SLC7A5GRM2LOXL2RAB9AHDAC1 | |
| SCHEMBL7247305 | 0.78 | GRM2 (0.43) | SLC7A5GRM2HDAC1HDAC3HDAC2 | |
| SCHEMBL8635430 | 0.76 | AKT1 (0.44) | SLC7A5GRM2HDAC1HDAC3HDAC2 | |
| SCHEMBL4398498 | 0.75 | RIPK1 (0.53) | GRM2AKT1HTTMEN1KMT2A | |
| SCHEMBL6690431 | 0.75 | BACE1 (0.41) | GRM2NPC1RAB9ASMN1; SMN2AKT1 | |
| SCHEMBL6676782 | 0.75 | BACE1 (0.41) | GRM2HDAC1HDAC3HDAC2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230190747-A1 | PHENYLOXADIAZOLE DERIVATIVES AS PGDS INHIBITORS | SANOFI SA (FR) | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230190747-A1 | PHENYLOXADIAZOLE DERIVATIVES AS PGDS INHIBITORS | PTGER1, PTGIS, PTGDR | SLC7A5 4500/4885GRM2 2256/4885LOXL2 1106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.