SCHEMBL2591384

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2591349	0.85	OPRK1 (0.46)	PDE9AGRM1KMT2A
	SCHEMBL2594585	0.83	OPRK1 (0.43)	PDE9AKDM5AKDM4CKDM5BHCAR3
	SCHEMBL30811759	0.83	RXRA (0.47)	KDM4CKDM4E
	SCHEMBL12498440	0.80	KDM5A (0.41)	PDE9AKDM5AKDM4CKDM5BHCAR3
	SCHEMBL2594124	0.79	KDM4E (0.48)	PDE9AKDM5AKDM4CKDM5BHCAR3
	SCHEMBL3465105	0.79	KDM4E (0.42)	PDE9AKDM5AKDM4CKDM5BHCAR3
	SCHEMBL20162102	0.78	PDE9A (0.41)	PDE9AKDM5AKDM4CKDM5BHCAR3
	SCHEMBL2587362	0.77	OPRK1 (0.39)	PDE9AKDM5AKDM4CKDM5BHCAR3
	SCHEMBL14716794	0.77	OPRK1 (0.39)	PDE9AKDM5AKDM4CKDM5BHCAR3
	SCHEMBL1407026	0.76	CNR2 (0.39)	KDM5AKDM4CKDM5BHCAR3GRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.