SCHEMBL2591387

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2591408	0.90	KMT2A (0.46)	PDE1APDE1BPDE1CKMT2ATSHR
	SCHEMBL20605033	0.89	MAOA (0.40)	KMT2ATSHRKDM4EMEN1GAA
	SCHEMBL20604997	0.86	CNR1 (0.39)	KMT2ATSHRKDM4EMEN1GAA
	SCHEMBL2588357	0.85	KMO (0.43)	PDE1APDE1BPDE1CKMT2AKDM4E
	SCHEMBL20604869	0.83	SMN1; SMN2 (0.45)	KMT2ATSHRKDM4EMEN1ALDH1A1
	SCHEMBL456891	0.82	CYP1A2 (0.42)	PDE1CKMT2AHSD17B10L3MBTL1OPRK1
	SCHEMBL20605332	0.82	CYP11B2 (0.35)	KMT2ATSHRKDM4EMEN1GAA
	SCHEMBL30790893	0.82	CYP11B2 (0.35)	KMT2ATSHRKDM4EMEN1GAA
	SCHEMBL29279380	0.81	SMN1; SMN2 (0.44)	TSHRKDM4EGAAHSD17B10ALDH1A1
	SCHEMBL15987446	0.79	CYP11B2 (0.48)	PDE1APDE1BPDE1CKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.