SCHEMBL25913957

SCHEMBL25913957

CC(=O)NC1C(O)OC(COCc2ccccc2)C(OC2OC(CO)C(OCc3ccccc3)C(O)C2OCc2ccccc2)C1OCc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ TP53 P04637 2/20 0.47
▸ MDM2 Q00987 2/20 0.47
▸ GJB2 P29033 4/20 0.47
▸ MDM4 O15151 1/20 0.45
▸ HSP90AA1 P07900 1/20 0.45
▸ HSP90AB1 P08238 1/20 0.45
▸ LGALS3 P17931 4/20 0.44
▸ LGALS7; LGALS7B P47929 2/20 0.43
▸ LGALS1 P09382 1/20 0.43
▸ LGALS9 O00182 1/20 0.43
▸ MAG P20916 1/20 0.42
▸ TACR2 P21452 1/20 0.42
▸ SLC6A2 P23975 1/20 0.42
▸ PTPN1 P18031 1/20 0.42
▸ GJA1 P17302 2/20 0.42
▸ MAPK1 P28482 1/20 0.42
▸ NT5E P21589 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25913933 0.87 GJB2 (0.48) GJB2SLC6A2GJA1NT5E
SCHEMBL15516519 0.87 TP53 (0.55) TP53MDM2MDM4HSP90AA1HSP90AB1
SCHEMBL6553315 0.86 LGALS3 (0.47) TP53MDM2LGALS3LGALS7; LGALS7BLGALS1
SCHEMBL11494535 0.86 MAG (0.49) TP53MDM2LGALS3LGALS7; LGALS7BLGALS1
SCHEMBL10704820 0.86 GJB2 (0.51) TP53MDM2GJB2MDM4HSP90AA1
SCHEMBL11170198 0.86 MAG (0.49) TP53MDM2LGALS3LGALS7; LGALS7BLGALS1
SCHEMBL11170193 0.86 MAG (0.49) TP53MDM2LGALS3LGALS7; LGALS7BLGALS1
SCHEMBL18867223 0.85 LMNA (0.52) TP53MDM2GJB2MDM4HSP90AA1
SCHEMBL7774709 0.84 MAPK1 (0.50) TP53MDM2MDM4HSP90AA1HSP90AB1
SCHEMBL25913950 0.84 LMNA (0.54) TP53MDM2MDM4HSP90AA1HSP90AB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230218766-A1 SUGAR COMPOUND HAVING POLYETHYLENE GLYCOL CHAIN, AND PRECURSOR OF ANTIBODY-DRUG COMPLEX THE NOGUCHI INSTITUTE (JP) 2023-07-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230218766-A1 SUGAR COMPOUND HAVING POLYETHYLENE GLYCOL CHAIN, AND PRECURSOR OF ANTIBODY-DRUG COMPLEX FCGRT, HBZ, FUT4 TP53 3889/4885MDM2 4657/4885GJB2 2030/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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