Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 3/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25323657 | 0.87 | PDK1 (0.39) | PDK2PDK1PDK3PDK4 | |
| SCHEMBL25326936 | 0.83 | PDK1 (0.37) | PDK2PDK1PDK3PDK4 | |
| SCHEMBL25327414 | 0.79 | PDK1 (0.34) | PDK2PDK1PDK3PDK4 | |
| SCHEMBL25326422 | 0.73 | RIPK1 (0.45) | PDK2PDK1PDK3PDK4 | |
| SCHEMBL25917117 | 0.72 | LIPE (0.33) | — | |
| SCHEMBL25327758 | 0.72 | HTR7 (0.36) | PDK2PDK1PDK3PDK4 | |
| SCHEMBL25916850 | 0.70 | PDK1 (0.41) | PDK2PDK1PDK3PDK4 | |
| SCHEMBL25918473 | 0.69 | HTT (0.30) | — | |
| SCHEMBL30522898 | 0.69 | RIPK1 (0.44) | PDK2PDK1PDK3PDK4 | |
| SCHEMBL25325665 | 0.68 | FABP7 (0.40) | PDK2PDK1PDK3PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146991-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |