Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | LPL | P06858 | 2/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25916636 | 0.81 | HTR2A (0.39) | LPLLIPG | |
| SCHEMBL21198134 | 0.73 | ROCK1 (0.41) | ROCK1LPLLIPG | |
| SCHEMBL15796068 | 0.68 | HDAC3 (0.43) | ROCK1LPLLIPG | |
| SCHEMBL3260141 | 0.67 | LPL (0.47) | LPLLIPG | |
| SCHEMBL15168853 | 0.67 | LPL (0.41) | LPLLIPG | |
| SCHEMBL25916640 | 0.66 | ROCK1 (0.38) | ROCK1LPLLIPG | |
| SCHEMBL31642273 | 0.66 | SIK2 (0.39) | ROCK1 | |
| SCHEMBL24504339 | 0.66 | LPL (0.42) | LPLLIPG | |
| SCHEMBL14315655 | 0.66 | LIPG (0.45) | LPLLIPG | |
| SCHEMBL4384473 | 0.65 | LPL (0.39) | LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023139379-A1 | MODULATORS OF RHO-ASSOCIATED PROTEIN KINASE (ROCK) | REDX PHARMA PLC (GB) | 2023-07-27 | — | — | WO | disclosed |