Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25916637 | 0.81 | ROCK1 (0.33) | LPLLIPG | |
| SCHEMBL25916643 | 0.80 | LPL (0.47) | CHRM1CHRM2CHRM3CHRNB4CHRNA3 | |
| SCHEMBL29554269 | 0.69 | MAPT (0.40) | HTR2ALPLLIPG | |
| SCHEMBL1934039 | 0.69 | MAPT (0.40) | HTR2ALPLLIPG | |
| SCHEMBL25916640 | 0.69 | ROCK1 (0.38) | LPLLIPG | |
| SCHEMBL27026510 | 0.69 | LPL (0.50) | LPLLIPG | |
| SCHEMBL29623555 | 0.69 | MAOA (0.43) | LPLLIPG | |
| SCHEMBL586732 | 0.69 | MAOA (0.43) | LPLLIPG | |
| SCHEMBL10224311 | 0.69 | P2RX7 (0.53) | CHRM1CHRM2CHRM3 | |
| SCHEMBL14305806 | 0.68 | LIPG (0.49) | LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023139379-A1 | MODULATORS OF RHO-ASSOCIATED PROTEIN KINASE (ROCK) | REDX PHARMA PLC (GB) | 2023-07-27 | — | — | WO | disclosed |