SCHEMBL25916693

SCHEMBL25916693

COc1ccc(N(C)C(=O)c2ccccc2)c(-c2nc3ccccc3s2)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.55
TP53 P04637 5/20 0.55
SMN1; SMN2 Q16637 5/20 0.54
RAB9A P51151 5/20 0.54
LMNA P02545 4/20 0.54
NPC1 O15118 3/20 0.54
CASP3 P42574 1/20 0.54
SENP8 Q96LD8 1/20 0.54
SENP7 Q9BQF6 1/20 0.54
SENP6 Q9GZR1 1/20 0.54
RXFP1 Q9HBX9 2/20 0.52
KDM4E B2RXH2 3/20 0.48
TDP1 Q9NUW8 2/20 0.48
NFKB1 P19838 1/20 0.48
NFKB2 Q00653 1/20 0.48
RELA Q04206 1/20 0.48
PKM P14618 1/20 0.48
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
ALDH1A1 P00352 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25916808 0.90 MAPT (0.50) MAPTTP53SMN1; SMN2RAB9ALMNA
SCHEMBL25916711 0.83 LMNA (0.50) MAPTTP53SMN1; SMN2RAB9ALMNA
SCHEMBL28201220 0.78 HSD17B2 (0.51) LMNAKDM4ETDP1MEN1KMT2A
SCHEMBL30362766 0.77 MAPT (0.77) MAPTTP53SMN1; SMN2RAB9ALMNA
SCHEMBL25916313 0.77 MAPT (0.77) MAPTTP53SMN1; SMN2RAB9ALMNA
SCHEMBL25916722 0.77 NPC1 (0.54) MAPTTP53SMN1; SMN2RAB9ALMNA
SCHEMBL25916333 0.76 MAPT (0.75) MAPTTP53SMN1; SMN2RAB9ALMNA
SCHEMBL30362804 0.76 MAPT (0.75) MAPTTP53SMN1; SMN2RAB9ALMNA
SCHEMBL5429408 0.75 MAPT (0.64) MAPTTP53SMN1; SMN2RAB9ALMNA
SCHEMBL30386590 0.75 MAPT (0.64) MAPTTP53SMN1; SMN2RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230235190-A1 FLUORESCENT COMPOSITION COMPRISING AT LEAST ONE BENZAZOLE COMPOUND FOR THE SECUREMENT OF PRODUCTS Crime Science Technology (FR) 2023-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230235190-A1 FLUORESCENT COMPOSITION COMPRISING AT LEAST ONE BENZAZOLE COMPOUND FOR THE SECUREMENT OF PRODUCTS TUBB3, TUBA3C, PHB1 MAPT 318/4885TP53 905/4885SMN1; SMN2 2121/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.