SCHEMBL25916722

SCHEMBL25916722

CCc1ccc(-c2nc3ccccc3s2)c(N(C)C(=O)c2ccccc2)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 7/20 0.54
RAB9A P51151 7/20 0.54
SMN1; SMN2 Q16637 4/20 0.54
TP53 P04637 3/20 0.54
LMNA P02545 2/20 0.54
CASP3 P42574 1/20 0.54
SENP8 Q96LD8 1/20 0.54
SENP7 Q9BQF6 1/20 0.54
SENP6 Q9GZR1 1/20 0.54
MAPT P10636 13/20 0.49
KDM4E B2RXH2 5/20 0.49
MEN1 O00255 4/20 0.49
KMT2A Q03164 4/20 0.49
ALDH1A1 P00352 1/20 0.49
HPGD P15428 1/20 0.49
RXFP1 Q9HBX9 2/20 0.45
POLB P06746 2/20 0.45
UBE2N P61088 1/20 0.45
BLM P54132 1/20 0.45
MMP2 P08253 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25916602 0.83 FSCN1 (0.42) NPC1RAB9ASMN1; SMN2LMNAMAPT
SCHEMBL25916808 0.80 MAPT (0.50) NPC1RAB9ASMN1; SMN2TP53LMNA
SCHEMBL25916693 0.77 MAPT (0.55) NPC1RAB9ASMN1; SMN2TP53LMNA
SCHEMBL17696371 0.71 AGPAT2 (0.52) NPC1RAB9ASMN1; SMN2LMNAMAPT
SCHEMBL12351738 0.71 RAB9A (1.00) NPC1RAB9ASMN1; SMN2TP53LMNA
SCHEMBL25916611 0.71 TP53 (0.55) NPC1RAB9ASMN1; SMN2TP53LMNA
SCHEMBL22259647 0.69 APP (0.62) NPC1RAB9ASMN1; SMN2TP53LMNA
SCHEMBL9296366 0.69 KDM4E (0.60) NPC1RAB9ASMN1; SMN2TP53LMNA
SCHEMBL29478093 0.68 MAPT (0.61) NPC1RAB9ASMN1; SMN2TP53LMNA
SCHEMBL28385011 0.68 MAPT (0.61) NPC1RAB9ASMN1; SMN2TP53LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230235190-A1 FLUORESCENT COMPOSITION COMPRISING AT LEAST ONE BENZAZOLE COMPOUND FOR THE SECUREMENT OF PRODUCTS Crime Science Technology (FR) 2023-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230235190-A1 FLUORESCENT COMPOSITION COMPRISING AT LEAST ONE BENZAZOLE COMPOUND FOR THE SECUREMENT OF PRODUCTS TUBB3, TUBA3C, PHB1 NPC1 1326/4885RAB9A 3041/4885SMN1; SMN2 2121/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.