Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.31 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25326693 | 0.81 | RIPK1 (0.36) | — | |
| SCHEMBL25325413 | 0.81 | RIPK1 (0.36) | — | |
| SCHEMBL25918545 | 0.79 | RORC (0.33) | SMN1; SMN2 | |
| SCHEMBL25915051 | 0.71 | TSHR (0.38) | TSHRMAPTGAASMN1; SMN2 | |
| SCHEMBL25918803 | 0.71 | SMN1; SMN2 (0.43) | TSHRMAPTGAASMN1; SMN2PIK3CD | |
| SCHEMBL25916905 | 0.69 | SIGMAR1 (0.34) | FFAR3 | |
| SCHEMBL26205557 | 0.67 | PIK3CD (0.36) | TSHRMAPTSMN1; SMN2PIK3CDPIK3R1 | |
| SCHEMBL30602637 | 0.66 | POLB (0.40) | PIK3CD | |
| Hydrochloric Acid SCHEMBL30602698 | 0.64 | POLB (0.39) | PIK3CD | |
| SCHEMBL25324800 | 0.63 | PRMT5 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146991-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |