SCHEMBL25916982

SCHEMBL25916982

CCCCCn1c(=O)n(CCCC[Si](OC)(OC)OC)c(=O)n(CCCC[Si](OC)(OC)OC)c1=O

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.43
ADORA2B P29275 2/20 0.41
TNF P01375 2/20 0.38
RGS4 P49798 2/20 0.37
PDE4A P27815 4/20 0.36
ADORA2A P29274 4/20 0.36
PDE4B Q07343 4/20 0.36
PDE4C Q08493 4/20 0.36
PDE4D Q08499 4/20 0.36
TLR8 Q9NR97 1/20 0.35
CNR2 P34972 1/20 0.35
PTGS1 P23219 3/20 0.35
PTGS2 P35354 3/20 0.35
MGLL Q99685 2/20 0.35
FAAH O00519 1/20 0.35
GSK3B P49841 1/20 0.35
RGS8 P57771 1/20 0.35
ADORA3 P0DMS8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3402639 0.93 LMNA (0.32) LMNAADORA2BPDE4AADORA2APDE4B
SCHEMBL9891728 0.91 RGS4 (0.42) LMNAADORA2BTNFRGS4PDE4A
SCHEMBL12164889 0.91 RGS4 (0.42) LMNAADORA2BTNFRGS4PDE4A
SCHEMBL3400000 0.91 LMNA (0.35) LMNAADORA2BTNFPDE4AADORA2A
SCHEMBL3402332 0.91 LMNA (0.35) LMNAADORA2BTNFPDE4AADORA2A
SCHEMBL3405710 0.91 LMNA (0.35) LMNAADORA2BTNFPDE4AADORA2A
SCHEMBL155052 0.87 LMNA (0.33) LMNAADORA2BTNFRGS4PDE4A
SCHEMBL12892325 0.83 PDE4A (0.33) LMNAADORA2BPDE4AADORA2APDE4B
SCHEMBL10015809 0.81 PDE4A (0.33) LMNAADORA2BTNFPDE4AADORA2A
SCHEMBL6239660 0.80 RGS4 (0.50) ADORA2BTNFRGS4PDE4AADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11873415-B2 Substrate with water repellent oil repellent layer, vapor deposition material, and method for producing substrate with water repellent oil repellent layer AGC Inc. (JP) 2024-01-16 US disclosed
US-20230220236-A1 COMPOSITION, SUBSTRATE WITH SURFACE LAYER, METHOD FOR PRODUCING SUBSTRATE WITH SURFACE LAYER, COMPOUNDS, AND METHODS FOR PRODUCING COMPOUNDS AGC Inc. (JP) 2023-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230220236-A1 COMPOSITION, SUBSTRATE WITH SURFACE LAYER, METHOD FOR PRODUCING SUBSTRATE WITH SURFACE LAYER, COMPOUNDS, AND METHODS FOR PRODUCING COMPOUNDS ZRANB2, ITGB1, ITGB2 LMNA 219/4885ADORA2B 591/4885TNF 2953/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.