Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 5/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.49 |
| ▸ | ERBB3 | P21860 | 3/20 | 0.49 |
| ▸ | ERBB4 | Q15303 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7597428 | 0.88 | L3MBTL1 (0.51) | STK39EGFRERBB2ERBB3ERBB4 | |
| SCHEMBL25472566 | 0.85 | TEAD1 (0.55) | NPSR1L3MBTL1MAPTTEAD1HTR2A | |
| SCHEMBL14586640 | 0.85 | NPSR1 (0.50) | NPSR1L3MBTL1MAPTTEAD1CYP1A2 | |
| SCHEMBL15832050 | 0.84 | L3MBTL1 (0.60) | STK39EGFRERBB2ERBB3ERBB4 | |
| SCHEMBL10538095 | 0.83 | NPSR1 (0.57) | STK39EGFRERBB2ERBB3ERBB4 | |
| SCHEMBL29638122 | 0.82 | EGFR (0.53) | STK39EGFRERBB2ERBB3ERBB4 | |
| SCHEMBL2747848 | 0.82 | EGFR (0.53) | STK39EGFRERBB2ERBB3ERBB4 | |
| SCHEMBL11121304 | 0.82 | STK39 (0.50) | STK39EGFRERBB2ERBB3ERBB4 | |
| SCHEMBL22225305 | 0.82 | STK39 (0.47) | STK39EGFRERBB2ERBB3ERBB4 | |
| SCHEMBL2749254 | 0.82 | STK39 (0.58) | STK39EGFRERBB2ERBB3ERBB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3350181-B1 | HER3 LIGANDS AND USES THEREOF | UNIV CALIFORNIA (US) | 2023-11-01 | — | — | EP | disclosed |
| WO-2023141635-A2 | HER3 LIGANDS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-07-27 | — | — | WO | disclosed |