Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTSR1 | P30989 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SDCBP | O00560 | 3/20 | 0.42 |
| ▸ | SDC2 | P34741 | 3/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | FASN | P49327 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25920245 | 0.93 | ALOX15 (0.43) | NTSR1ALOX15MAPTSMN1; SMN2KDM4E | |
| SCHEMBL25920284 | 0.91 | NPC1 (0.43) | NTSR1MAPTSMN1; SMN2SDCBPSDC2 | |
| SCHEMBL25919934 | 0.88 | CYP11B1 (0.49) | NTSR1ALOX15MAPTSMN1; SMN2KDM4E | |
| SCHEMBL25918414 | 0.88 | ALOX15 (0.50) | ALOX15MAPTSMN1; SMN2KDM4ESDCBP | |
| SCHEMBL25920244 | 0.85 | NPC1 (0.43) | MAPTSMN1; SMN2SDCBPSDC2MAPK1 | |
| SCHEMBL25330849 | 0.84 | NTSR1 (0.40) | NTSR1SDCBPSDC2CHEK1MAPK1 | |
| SCHEMBL30477293 | 0.84 | NTSR1 (0.40) | NTSR1SDCBPSDC2CHEK1MAPK1 | |
| SCHEMBL25918495 | 0.82 | MAP3K5 (0.47) | ALOX15MAPTSMN1; SMN2KDM4ESDCBP | |
| SCHEMBL25921545 | 0.80 | ALOX15 (0.50) | NTSR1ALOX15MAPTSMN1; SMN2KDM4E | |
| SCHEMBL25919933 | 0.79 | CYP11B1 (0.46) | NTSR1SMN1; SMN2MAPK1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023132606-A1 | NOVEL ISOINDOLINONE DERIVATIVE COMPOUNDS AS CASPASE INHIBITORS | 주식회사 이노보테라퓨틱스 | 2023-07-13 | — | — | WO | disclosed |