Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 9/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 9/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SDCBP | O00560 | 1/20 | 0.43 |
| ▸ | SDC2 | P34741 | 1/20 | 0.43 |
| ▸ | WNT1 | P04628 | 2/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25919933 | 0.91 | CYP11B1 (0.46) | CYP11B1CYP11B2SMN1; SMN2ROCK2NAMPT | |
| SCHEMBL25920286 | 0.88 | NTSR1 (0.45) | CYP11B1CYP11B2ALOX15MAPTSMN1; SMN2 | |
| SCHEMBL25918414 | 0.88 | ALOX15 (0.50) | ALOX15MAPTSMN1; SMN2KDM4ESDCBP | |
| SCHEMBL25331325 | 0.84 | MAPK1 (0.42) | CYP11B1CYP11B2ROCK2NAMPTCREBBP | |
| SCHEMBL30477299 | 0.84 | MAPK1 (0.42) | CYP11B1CYP11B2ROCK2NAMPTCREBBP | |
| SCHEMBL25920245 | 0.83 | ALOX15 (0.43) | ALOX15MAPTSMN1; SMN2KDM4ENTSR1 | |
| SCHEMBL25918382 | 0.81 | SDCBP (0.55) | ALOX15MAPTSMN1; SMN2KDM4ESDCBP | |
| SCHEMBL25920056 | 0.80 | ACVR1 (0.44) | ALOX15MAPTSMN1; SMN2CREBBPKDM4E | |
| SCHEMBL25918495 | 0.79 | MAP3K5 (0.47) | CYP11B1CYP11B2ALOX15MAPTSMN1; SMN2 | |
| SCHEMBL25921545 | 0.79 | ALOX15 (0.50) | ALOX15MAPTSMN1; SMN2KDM4ENTSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023132606-A1 | NOVEL ISOINDOLINONE DERIVATIVE COMPOUNDS AS CASPASE INHIBITORS | 주식회사 이노보테라퓨틱스 | 2023-07-13 | — | — | WO | disclosed |