Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27480557 | 0.86 | ALDH1A1 (0.48) | CHRM2CHRM1CHRM3ALDH1A1NPC1 | |
| SCHEMBL25920678 | 0.86 | ALDH1A1 (0.48) | CHRM2CHRM1CHRM3ALDH1A1NPC1 | |
| SCHEMBL25920400 | 0.84 | RAB9A (0.53) | CHRM2CHRM1CHRM3ALDH1A1NPC1 | |
| SCHEMBL2563366 | 0.82 | HSD11B1 (0.50) | MAOBALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL13915755 | 0.82 | ALDH1A1 (0.46) | CHRM2CHRM1CHRM3MAOBALDH1A1 | |
| SCHEMBL10157569 | 0.82 | GABRP (0.46) | CHRM2CHRM1CHRM3ALDH1A1NPC1 | |
| SCHEMBL25920624 | 0.82 | CHRM2 (0.44) | CHRM2CHRM1CHRM3MAOBALDH1A1 | |
| SCHEMBL25920560 | 0.81 | ALDH1A1 (0.47) | MAOBALDH1A1NPC1GLAHTT | |
| SCHEMBL27476357 | 0.79 | MEN1 (0.44) | MAOBALDH1A1NPC1HTTRAB9A | |
| SCHEMBL3336342 | 0.78 | GAA (0.50) | CHRM2CHRM1CHRM3ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242496-A1 | SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242496-A1 | SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA | BCL6, SOX18, BCL3 | CHRM2 4873/4885CHRM1 4876/4885CHRM3 4841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.