Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25919979 | 0.76 | AR (0.39) | NPC1MAPTRAB9ASMN1; SMN2THRA | |
| SCHEMBL25314684 | 0.74 | ALOX5AP (0.40) | NPC1MAPTRAB9ASMN1; SMN2THRA | |
| SCHEMBL25317633 | 0.71 | THRA (0.47) | MAPTRAB9ATHRATHRBPTGES | |
| SCHEMBL25317121 | 0.71 | DRD2 (0.40) | NPC1RAB9A | |
| SCHEMBL25317341 | 0.71 | THRA (0.37) | NPC1MAPTRAB9ASMN1; SMN2THRA | |
| SCHEMBL25316793 | 0.70 | PDIA6 (0.36) | NPC1MAPTRAB9ASMN1; SMN2THRA | |
| SCHEMBL4332998 | 0.68 | LTA4H (0.50) | PPARAMAOBCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7010616 | 0.68 | ALDH1A1 (0.44) | NPC1MAPTRAB9ASMN1; SMN2THRB | |
| SCHEMBL14434929 | 0.68 | IDO1 (0.42) | AR | |
| SCHEMBL19649433 | 0.67 | PDK2 (0.46) | MAPTTHRATHRBGPR84PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141432-A2 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS, INC. (US) | 2023-07-27 | — | — | WO | disclosed |