Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21088883 | 0.87 | KDM1A (0.44) | SMN1; SMN2ITGB3ITGA2BPOLBHTT | |
| SCHEMBL25923992 | 0.85 | L3MBTL1 (0.40) | L3MBTL1SMN1; SMN2POLBHTTKDM1A | |
| SCHEMBL25923906 | 0.80 | KDM1A (0.46) | SMN1; SMN2KDM1AKDM4ELMNAKMT2A | |
| SCHEMBL21088467 | 0.79 | CNR1 (0.37) | SMN1; SMN2KDM1A | |
| SCHEMBL25923937 | 0.77 | KDM1A (0.40) | KDM1A | |
| SCHEMBL25924008 | 0.76 | KDM1A (0.32) | KDM1A | |
| SCHEMBL31269932 | 0.74 | L3MBTL1 (0.62) | L3MBTL1SMN1; SMN2ITGB3ITGA2BPOLB | |
| SCHEMBL31269835 | 0.74 | L3MBTL1 (0.62) | L3MBTL1SMN1; SMN2ITGB3ITGA2BPOLB | |
| SCHEMBL25923925 | 0.73 | KDM1A (0.42) | KDM1A | |
| SCHEMBL31270000 | 0.73 | L3MBTL1 (0.66) | L3MBTL1SMN1; SMN2ITGB3ITGA2BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3532459-B1 | LSD1 INHIBITORS AND MEDICAL USES THEREOF | CONSTELLATION PHARMACEUTICALS INC (US) | 2023-08-02 | — | — | EP | disclosed |