Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 7/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25924012 | 0.87 | L3MBTL1 (0.45) | KDM1AITGB3ITGA2BSMN1; SMN2MAPK1 | |
| SCHEMBL21088777 | 0.84 | KDM1A (0.40) | KDM1AITGB3ITGA2BGLAAPEX1 | |
| SCHEMBL25923906 | 0.81 | KDM1A (0.46) | KDM1ASMN1; SMN2 | |
| SCHEMBL21088467 | 0.80 | CNR1 (0.37) | KDM1ASMN1; SMN2 | |
| SCHEMBL25923937 | 0.78 | KDM1A (0.40) | KDM1ACYP1A2 | |
| SCHEMBL21088867 | 0.75 | HTR4 (0.35) | KDM1A | |
| SCHEMBL29326474 | 0.75 | ITGB3 (0.43) | KDM1AITGB3ITGA2BGLASMN1; SMN2 | |
| SCHEMBL25923925 | 0.74 | KDM1A (0.42) | KDM1ACYP1A2 | |
| SCHEMBL25924008 | 0.74 | KDM1A (0.32) | KDM1A | |
| SCHEMBL21088586 | 0.73 | KDM1A (0.31) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3286172-B1 | LSD1 INHIBITORS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS INC (US) | 2019-06-12 | — | — | EP | disclosed |