Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25923937 | 0.90 | KDM1A (0.40) | KDM1A | |
| SCHEMBL20106792 | 0.82 | KDM1A (0.44) | KDM1APKMKMT2A | |
| SCHEMBL21088883 | 0.81 | KDM1A (0.44) | KDM1ASMN1; SMN2 | |
| SCHEMBL25924012 | 0.80 | L3MBTL1 (0.45) | KDM1AKMT2AKDM4ESMN1; SMN2LMNA | |
| SCHEMBL25924008 | 0.79 | KDM1A (0.32) | KDM1A | |
| SCHEMBL25923925 | 0.79 | KDM1A (0.42) | KDM1AHSD11B1 | |
| SCHEMBL25923950 | 0.78 | MAPT (0.44) | KDM1AKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL24940732 | 0.76 | KMT2A (0.31) | KDM1AKMT2A | |
| SCHEMBL25923931 | 0.76 | HTR4 (0.33) | KDM1A | |
| SCHEMBL21088586 | 0.75 | KDM1A (0.31) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3532459-B1 | LSD1 INHIBITORS AND MEDICAL USES THEREOF | CONSTELLATION PHARMACEUTICALS INC (US) | 2023-08-02 | — | — | EP | disclosed |