Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.32 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.32 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.31 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25923906 | 0.79 | KDM1A (0.46) | KDM1AHSD11B1 | |
| SCHEMBL24378839 | 0.78 | HSD11B1 (0.42) | KDM1AHSD11B1CYP1A2CYP2D6ALOX15 | |
| SCHEMBL23588963 | 0.77 | HSD11B1 (0.44) | KDM1AHSD11B1HTR4CYP2D6 | |
| SCHEMBL25923937 | 0.76 | KDM1A (0.40) | KDM1AGNAI3GNAO1GNAI1CYP1A2 | |
| SCHEMBL24940732 | 0.76 | KMT2A (0.31) | KDM1A | |
| SCHEMBL25924008 | 0.75 | KDM1A (0.32) | KDM1A | |
| SCHEMBL21088883 | 0.74 | KDM1A (0.44) | KDM1ACYP1A2 | |
| SCHEMBL25924012 | 0.73 | L3MBTL1 (0.45) | KDM1A | |
| SCHEMBL21088467 | 0.73 | CNR1 (0.37) | KDM1A | |
| SCHEMBL25001376 | 0.72 | HSD11B1 (0.38) | KDM1AHSD11B1CYP1A2CYP2D6ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3532459-B1 | LSD1 INHIBITORS AND MEDICAL USES THEREOF | CONSTELLATION PHARMACEUTICALS INC (US) | 2023-08-02 | — | — | EP | disclosed |