SCHEMBL25924008

SCHEMBL25924008

NSCCN1CCC2(CC1)CC(NC1CC1)C2

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20106817 0.84 KDM1A (0.30) KDM1A
SCHEMBL25923906 0.79 KDM1A (0.46) KDM1A
SCHEMBL25923937 0.76 KDM1A (0.40) KDM1A
SCHEMBL25924012 0.76 L3MBTL1 (0.45) KDM1A
SCHEMBL25923925 0.75 KDM1A (0.42) KDM1A
SCHEMBL21088883 0.74 KDM1A (0.44) KDM1A
SCHEMBL24940732 0.72 KMT2A (0.31) KDM1A
SCHEMBL21088586 0.71 KDM1A (0.31) KDM1A
SCHEMBL25923931 0.69 HTR4 (0.33) KDM1A
SCHEMBL21088400 0.68 KDM1A (0.32) KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3532459-B1 LSD1 INHIBITORS AND MEDICAL USES THEREOF CONSTELLATION PHARMACEUTICALS INC (US) 2023-08-02 EP disclosed