SCHEMBL25925007

SCHEMBL25925007

CCN1Cc2ccc(C)c(F)c2C(F)(F)C1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 1/20 0.36
KIF11 P52732 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25924943 0.72 ALDH1A1 (0.34)
SCHEMBL23346036 0.68
SCHEMBL25924944 0.65 L3MBTL3 (0.36) HTR2C
SCHEMBL18826496 0.59
SCHEMBL14163034 0.59 KCNH2 (0.47)
SCHEMBL13939999 0.58 KIF11 (0.44) HTR2CKIF11
SCHEMBL25555565 0.58 MAPT (0.43) HTR2C
SCHEMBL20348542 0.58 CYP19A1 (0.40) HTR2C
SCHEMBL18376160 0.58 HTR2C (0.50) HTR2CKIF11
SCHEMBL26391557 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023109892-A1 COMPOUND FOR INHIBITING OR DEGRADING BRD9, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF 海思科医药集团股份有限公司 2023-06-22 WO disclosed