Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.56 |
| ▸ | ADCY1 | Q08828 | 5/20 | 0.51 |
| ▸ | ADCY8 | P40145 | 2/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.47 |
| ▸ | APLNR | P35414 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | CCR6 | P51684 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25927861 | 0.77 | KMT2A (0.57) | HDAC6NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL25928107 | 0.75 | ALDH1A1 (0.41) | HDAC6NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL18804048 | 0.72 | FABP4 (0.59) | NPC1RAB9AKDM4ESMN1; SMN2LMNA | |
| SCHEMBL25928142 | 0.72 | ADORA3 (0.44) | HDAC6NPC1RAB9ASMN1; SMN2ALOX15 | |
| SCHEMBL25929182 | 0.72 | HDAC6 (0.42) | HDAC6NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL18872357 | 0.70 | FABP4 (0.66) | ABCG2NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL8770855 | 0.70 | NPC1 (0.74) | HDAC6ADCY1ABCG2NPC1RAB9A | |
| SCHEMBL12171414 | 0.69 | NPC1 (0.96) | HDAC6ADCY1ADCY8NPC1RAB9A | |
| SCHEMBL24473971 | 0.69 | ADCY1 (0.74) | HDAC6ADCY1ADCY8NPC1RAB9A | |
| SCHEMBL24474019 | 0.69 | KDM4E (0.74) | HDAC6ADCY1ADCY8ABCG2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023138254-A1 | HETEROCYCLIC COMPOUND, AND ORGANIC ELECTROLUMINESCENT MATERIAL AND ELEMENT | 上海八亿时空先进材料有限公司 | 2023-07-27 | — | — | WO | disclosed |