Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | PAM | P19021 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 4/20 | 0.32 |
| ▸ | GABRD | O14764 | 4/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.32 |
| ▸ | GABRE | P78334 | 4/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.32 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.32 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.32 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8755819 | 0.88 | ALDH1A1 (0.48) | ALDH1A1CYP2D6ALOX15PAM | |
| SCHEMBL8755829 | 0.88 | ALDH1A1 (0.48) | ALDH1A1CYP2D6ALOX15PAM | |
| SCHEMBL12973054 | 0.84 | — | — | |
| SCHEMBL1130559 | 0.84 | — | — | |
| SCHEMBL586254 | 0.84 | — | — | |
| SCHEMBL8733627 | 0.82 | — | — | |
| SCHEMBL8733629 | 0.82 | — | — | |
| SCHEMBL6646941 | 0.80 | ALDH1A1 (0.50) | ALDH1A1CYP2D6ALOX15PAMCYP1A2 | |
| SCHEMBL10988448 | 0.80 | — | — | |
| SCHEMBL6646944 | 0.80 | ALDH1A1 (0.50) | ALDH1A1CYP2D6ALOX15PAMCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230241019-A1 | ELECTROPHILIC COMPOUNDS AND ELECTROPHILIC PRODRUGS FOR TREATING ANEURYSM | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2023-08-03 | — | — | US | disclosed |
| US-11642325-B2 | Prevention, treatment and reversal of disease using therapeutically effective amounts of dicarboxylic acid compounds | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2023-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11642325-B2 | Prevention, treatment and reversal of disease using therapeutically effective amounts of dicarboxylic acid compounds | PC, FH, SLC25A20 | ALDH1A1 243/4885CYP2D6 844/4885ALOX15 724/4885 |
| US-20230241019-A1 | ELECTROPHILIC COMPOUNDS AND ELECTROPHILIC PRODRUGS FOR TREATING ANEURYSM | AADAC, FFAR2, GSTO1 | ALDH1A1 364/4885CYP2D6 400/4885ALOX15 33/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.