Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.43 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | WHR1 | P49842 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24215208 | 0.83 | SCN10A (0.44) | SCN10AMBOAT4OPRK1SIGMAR1PIK3CA | |
| SCHEMBL30412557 | 0.81 | TRPV1 (0.42) | SCN10AMBOAT4PDE10ACHRM3PDE4A | |
| SCHEMBL22803865 | 0.81 | TRPV1 (0.42) | SCN10AMBOAT4PDE10ACHRM3PDE4A | |
| SCHEMBL2366907 | 0.79 | HRH4 (0.48) | — | |
| SCHEMBL30593370 | 0.79 | HRH4 (0.48) | — | |
| SCHEMBL1745337 | 0.78 | KDM4E (0.36) | OPRK1PIK3CAMTORFLT3 | |
| SCHEMBL15351824 | 0.78 | SCN10A (0.36) | SCN10APDE10ASIGMAR1PIK3CAMTOR | |
| SCHEMBL24225614 | 0.78 | ALDH1A3 (0.37) | SCN10APDE10ASIGMAR1PIK3CAMTOR | |
| SCHEMBL1707795 | 0.78 | ALDH1A1 (0.44) | OPRK1PDE10APIK3CAMTOR | |
| SCHEMBL21905951 | 0.77 | OPRK1 (0.57) | SCN10AOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131271-A1 | PYRROLE FUSED-RING PYRAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 杭州中美华东制药有限公司 | 2023-07-13 | — | — | WO | disclosed |