Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 5/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | MERTK | Q12866 | 1/20 | 0.34 |
| ▸ | MAP3K7 | O43318 | 6/20 | 0.34 |
| ▸ | TAB1 | Q15750 | 6/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 3/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25928954 | 0.91 | MET (0.39) | METBRD4AXLMERTKMAP3K7 | |
| SCHEMBL25929941 | 0.90 | FFAR2 (0.34) | METBRD4AXLMERTKMAP3K7 | |
| SCHEMBL25927465 | 0.82 | MET (0.39) | METBRD4AXLMERTKMAP3K7 | |
| SCHEMBL25931437 | 0.82 | KHK (0.35) | METAXLMERTKMAP3K7TAB1 | |
| SCHEMBL25929297 | 0.80 | HTR6 (0.40) | METBRD4AXLMERTKMAP3K7 | |
| SCHEMBL25927872 | 0.80 | JAK2 (0.38) | METBRD4AXLMERTKMAP3K7 | |
| SCHEMBL25923438 | 0.79 | PDPK1 (0.44) | METPAK1 | |
| SCHEMBL25928430 | 0.79 | MET (0.37) | METBRD4AXLMERTKMAP3K7 | |
| SCHEMBL25924810 | 0.79 | MET (0.40) | METBRD4AXLMERTKMAP3K7 | |
| SCHEMBL25930106 | 0.78 | MET (0.37) | METBRD4AXLMERTKMAP3K7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131271-A1 | PYRROLE FUSED-RING PYRAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 杭州中美华东制药有限公司 | 2023-07-13 | — | — | WO | disclosed |