Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 2/20 | 0.48 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 3/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7010865 | 0.92 | ALDH1A1 (0.47) | ITGA4ITGB7ALDH1A1P2RX7LMNA | |
| SCHEMBL16700988 | 0.84 | ALDH1A1 (0.45) | ITGA4ITGB7ALDH1A1P2RX7LMNA | |
| SCHEMBL25062469 | 0.83 | OPRM1 (0.53) | ALDH1A1P2RX7APOBEC3AAPOBEC3GLMNA | |
| SCHEMBL29430547 | 0.83 | OPRM1 (0.53) | ALDH1A1P2RX7APOBEC3AAPOBEC3GLMNA | |
| SCHEMBL5653608 | 0.82 | ITGA4 (0.47) | ITGA4ITGB7ALDH1A1P2RX7APOBEC3A | |
| SCHEMBL30475673 | 0.81 | ALDH1A1 (0.47) | ITGA4ITGB7ALDH1A1P2RX7LMNA | |
| SCHEMBL25062470 | 0.81 | ALDH1A1 (0.47) | ITGA4ITGB7ALDH1A1P2RX7LMNA | |
| SCHEMBL17896072 | 0.81 | AKR1C1 (0.62) | ITGA4ITGB7ALDH1A1P2RX7LMNA | |
| SCHEMBL16700032 | 0.81 | ALDH1A1 (0.43) | ITGA4ITGB7ALDH1A1P2RX7LMNA | |
| SCHEMBL1038755 | 0.81 | HDAC4 (0.62) | ALDH1A1P2RX7CHRM3APOBEC3AAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117651701-A | Novel substituted bicyclic aza heterocycles as SOS1 inhibitors | 唯久生物技术(苏州)有限公司 | 2024-03-05 | — | — | CN | disclosed |
| WO-2011134877-A1 | HETEROBIARYL-CYCLOHEXYL-TETRAAZABENZO[E]AZULENES | F. HOFFMANN-LA ROCHE AG (CH) | 2011-11-03 | — | — | WO | disclosed |