Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | VNN1 | O95497 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25062470 | 1.00 | ALDH1A1 (0.47) | ALDH1A1P2RX7AKR1C1LMNANPSR1 | |
| SCHEMBL1574935 | 0.97 | IDO1 (0.46) | ALDH1A1P2RX7AKR1C1LMNANPSR1 | |
| SCHEMBL9338162 | 0.85 | AKR1C1 (0.65) | ALDH1A1P2RX7AKR1C1LMNANPSR1 | |
| SCHEMBL89653 | 0.83 | OPRM1 (0.47) | ALDH1A1P2RX7AKR1C1LMNANPSR1 | |
| SCHEMBL17896072 | 0.83 | AKR1C1 (0.62) | ALDH1A1P2RX7AKR1C1LMNANPSR1 | |
| SCHEMBL27925690 | 0.83 | ALDH1A1 (0.46) | ALDH1A1P2RX7AKR1C1LMNANPSR1 | |
| SCHEMBL25460767 | 0.83 | ALDH1A1 (0.53) | ALDH1A1P2RX7AKR1C1LMNANPSR1 | |
| SCHEMBL3664975 | 0.82 | LMNA (0.47) | ALDH1A1P2RX7AKR1C1LMNANPSR1 | |
| SCHEMBL15823293 | 0.82 | LMNA (0.47) | ALDH1A1P2RX7AKR1C1LMNANPSR1 | |
| SCHEMBL2593341 | 0.81 | ITGA4 (0.48) | ALDH1A1P2RX7AKR1C1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116234800-A | Copper complexes for the treatment of neurodegenerative disorders | ALS治疗发展学会 | 2023-06-06 | — | — | CN | disclosed |