SCHEMBL25937459

SCHEMBL25937459

CN1C(=O)C(CO)N(C)C(=O)C1CO

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CAPN1 P07384 1/20 0.47
BRD4 O60885 2/20 0.37
ADRA2C P18825 1/20 0.35
MGAM O43451 1/20 0.35
MAPK1 P28482 1/20 0.32
KMT2A Q03164 1/20 0.31
KDM4E B2RXH2 1/20 0.31
GLA P06280 1/20 0.31
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25937418 0.91 CAPN1 (0.41) CAPN1BRD4MGAMKDM4EGLA
SCHEMBL503017 0.80 KDM4E (0.38) CAPN1BRD4ADRA2CMGAMMAPK1
SCHEMBL4778463 0.77 HDAC6 (0.35) CAPN1BRD4ADRA2CMAPK1L3MBTL1
SCHEMBL25937442 0.74 CAPN1 (0.43) CAPN1BRD4ADRA2CKMT2AKDM4E
SCHEMBL16026458 0.74 CAPN1 (0.33) CAPN1MAPTL3MBTL1
SCHEMBL11999052 0.72 ADRA2C (0.48) BRD4ADRA2CMGAMMAPK1KMT2A
Dioxane SCHEMBL9486523 0.71 KDM4E (0.36) BRD4KMT2AKDM4EALDH1A1MAPT
SCHEMBL17360666 0.70 CAPN1 (0.41) CAPN1KDM4E
SCHEMBL26303973 0.70 CAPN1 (0.41) CAPN1ADRA2CKMT2A
SCHEMBL10501254 0.69 KDM4E (0.35) KMT2AKDM4EALDH1A1MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230242491-A1 DIMERS FROM BIOREACHABLE MOLECULES AS COPOLYMERS ZYMERGEN INC. (US) 2023-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242491-A1 DIMERS FROM BIOREACHABLE MOLECULES AS COPOLYMERS HDHD5, HAO2, ALAD CAPN1 3978/4885BRD4 4404/4885ADRA2C 4440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.